• Post-DSAEK transepi topo- PRK. How to improve refraction and optical quality Description: Safety and efficacy of tPRK treatments after DSAEK, is demonstrated in cases that underwent tPRK 8-18 months following DSAEK. Surgical planning, technique and post-op management will be demonstrated along with peri-operative UDVA, CDVA, refractive, keratometric, topography and tomography data by Scheimpflug and anterior segment OCT up to 120 months. Mean values changes: UDVA from 20/50 to 20/26, CDVA 20/30 to 20/16, no eyes lost lines of CDVA. All imaging data to include epithelial thickness map normality improved by month 3. tPRK after DSAEK appears to be safe and very effective in improving visual function. Therapeutic improvement of the scarred anterior corneal surface of the host may also enhance the refractive correction. DSAEK may manifest significant refractive errors after host cornea-deturgescence tPRK may not only offer safe and effective improvement, of even complex corneal and refractive irregularities, it can also improve host corneal clarity. Subspecialty: Refractive Management / Intervention Level: Intermediate Uploaded By: A. Kanellopoulos